Increased plasma glucose, lipid profile (except HDL), insulin, insulin resistance, MDA, and ADMA but decreased HDL, PON-1 and DDAH were also observed. Results: The high fat diet group had greater body weight and higher SBP as compared to control rats. Methods: Sixty male Wistar rats were randomly divided into six groups (n=10) for 8 weeks three groups of them received standard diet with either vehicle or taurine (3% w/v in drinking water) or telmisartan (5 mg/kg, oral) while the other three groups received high fat diet with either vehicle or taurine or telmisartan. So, this study aimed to compare between telmisartan and taurine supplementation on systolic blood pressure (SBP) in addition to some metabolic disturbances and some vascular complications in an animal model for obesity. Future studies are needed to establish the effects of oral taurine supplementation on targeted pathologies and the optimal supplementation doses and periods.Obesity, insulin resistance, hypertension and fatty liver, are key risk factors for vascular complications. These results translated to mean ~ 3 mmHg reductions in both SBP (range = 0–15 mmHg) and DBP (range = 0–7 mmHg) following a range of doses (1 to 6 g/day) and supplementation periods (1 day to 12 weeks), with no adverse events reported.SummaryThese preliminary findings suggest that ingestion of taurine at the stated doses and supplementation periods can reduce blood pressure to a clinically relevant magnitude, without any adverse side effects. There were seven peer-reviewed studies meeting the inclusion criteria, encompassing 103 participants of varying age and health statuses. A search was performed using various databases in May 2018 and later screened using search criteria for eligibility. However, these investigations have been conducted across a number of decades and populations and have not been collectively reviewed. Purpose of ReviewThe aims of this meta-analysis were to investigate the effects of orally administered isolated taurine on resting systolic blood pressure (SBP) and diastolic blood pressure (DBP) in humans.Recent FindingsThere is growing evidence that taurine deficiency is associated with hypertension and that oral supplementation can have antihypertensive effects in humans. Swansea University Medical School (558).Swansea University Medical School (6828).School of Business and Economics Administration (9).Operations Management and Entrepreneurship (294).Human Resource Management and Organisational Studies (57).Research Engagement and Innovation Services (129).Legal Practice and Graduate Diploma Law (6).Hillary Rodham Clinton School of Law (3).Hillary Rodham Clinton School of Law (1416).Swansea Centre for Health Economics (138). College of Human and Health Sciences (205).Centre for Social Work and Social Care Research (59).College of Human and Health Sciences (4810).Research Institute for Arts and Humanities (2).Modern Languages, Translation and Interpreting (56).Languages, Translation and Communication (105).Languages, Translation And Communication (37).English Literature and Creative Writing (130).English Language and Applied Linguistics (59).Classics, Ancient History and Egyptology (249).
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |